|
|
|
Research Intelligence Platform
Your Research Digest
22 October 2026 · 10 new publications
|
|
Matched against your profile
Global burden of disorders affecting the… · Global burden and strength of evidence fo… · Self-assessed driving skills and risky dr… · Global all-cause mortality and life expec… · Global burden and projections of other mu…
|
|
| 01
|
Global burden of disorders affecting the nervous…
C. Sun, S. Wei & J. Tao et al. | 2026
Advanced
Science |
Q1 · 99th percentile in Biochemistry, Genetics and Molecular Biology (miscellaneous)
The study integrated GBD epidemiological data (1990–2021) with genotype data from 2.6M SNPs across 2414 individuals in 20 countries to identify 1,074 burden QTLs for IBD (384 linked to both prevalence and incidence), highlighted rs7633471 as the strongest signal,
and fine-mapped 800 putative causal variants in genes tied to immunity, inflammation, and intestinal cancer; pathway analysis showed enrichment in synaptic membrane and potassium channel complexes.
|
Why it matters
Because the bQTLs are enriched for synaptic membrane and voltage-gated potassium channel pathways and the paper demonstrates a scalable approach linking population genetics to disease burden across countries, these results are relevant for understanding geographic
heterogeneity and potential neuro-immune mechanisms impacting the global burden of nervous system disorders.
|
Read
the paper → |
|
|
|
| 02
|
Global all-cause mortality and life expectancy es…
T. Li, P. Charalampous & S. Lubbe et al. | 2026
| Vol. 11, Issue 10
The
Lancet Public Health |
Q1 · 99th percentile in Public Health, Environmental and Occupational Health
The GBD 2023 analysis for ASEAN reports 2023 regional life expectancy of 70.1 years for males and 76.2 years for females with large country variation (female Singapore 87.5, male Myanmar 62.1); causes shift by age—neonatal disorders in infancy, road injuries
driving male adolescent deaths, maternal disorders for women 25–34, and ischaemic heart disease and stroke in mid-adulthood—while tobacco (males) and high blood pressure (females) are dominant risks.
|
Why it matters
These age‑sex‑country cause and risk decompositions offer granular data to validate and refine your GBD all-cause mortality and life‑expectancy estimates (1950–2023) and to identify persistent regional inequalities important for trend analyses and model calibration.
|
Read
the paper → |
|
|
|
| 03
|
Global all-cause mortality and life expectancy es…
D. Areda, H. Kim & J. Kang et al. | 2026
| Vol. 100
EClinicalMedicine
|
Q1 · 97th percentile in Medicine (all)
GBD 2023 estimates show global age-standardized tetanus incidence fell by 93.8% and DALY rates by 95.4% between 1990 and 2023, yet substantial, avoidable burden persists in sub-Saharan Africa, South Asia and in countries like Somalia, Laos and Chad and is concentrated
among neonates and males. The burden is strongly inversely associated with Socio-demographic Index (SDI), with near-zero rates in high-income settings.
|
Why it matters
Tetanus’ steep global decline but persistent, regionally concentrated contribution to deaths and DALYs in low-SDI populations will directly affect cause-specific components of all-cause mortality and life-expectancy estimates across 1950–2023 and should be
accounted for in your modelling and uncertainty assessments.
|
Read
the paper → |
|
|
|
| 04
|
Global burden of disorders affecting the nervous…
D. Iskakova, B. İlçe & A. Kamzanova et al. | 2026
| Vol. 20
Frontiers
in Integrative Neuroscience |
Q1 · 94th percentile in Sensory Systems
This integrative review shows that major depressive disorder reflects both molecular dysregulation (neuroplasticity, stress pathways, neuroinflammation, oxidative stress, neurotransmitter changes) and dysfunction of large-scale brain networks, while direct
multimodal links across these levels are still limited. The authors conclude that integrating neuroimaging and molecular approaches could improve biomarker discovery, patient stratification, and treatment response prediction.
|
Why it matters
For GBD 1990–2021 work, these findings underscore biological heterogeneity and the need for objective, multimodal biomarkers to refine case definitions, improve burden estimates, and target interventions across populations.
|
Read
the paper → |
|
|
|
| 05
|
Global burden of disorders affecting the nervous…
Z. Xie, Z. Xie & C. Sun et al. | 2026
| Vol. 29, Issue 11
iScience
|
Q1 · 89th percentile in Multidisciplinary
Using GBD data and ClinVar, the study found that age-standardized prevalence and DALY rates for four rare childhood neurological diseases increased from 1990–2021, were higher among boys and in low–middle SDI countries, and are projected to affect 110.2 thousand
children by 2050 (an 11.8% rise); genetic analyses also show rising numbers of disease-causing genes and pathogenic variants through 2024.
|
Why it matters
For a researcher on the global burden of nervous system disorders, these results quantify increasing pediatric neurological disease burden and socio-demographic disparities and highlight growing genetic knowledge that should inform future GBD estimates and
targeted prevention strategies.
|
Read
the paper → |
|
|
|
| 06
|
Self-assessed driving skills and risky driving be…
M. Saadati, S. Doulati & R. Yari | 2026
| Vol. 12, Issue 16
Heliyon
|
Q1 · 89th percentile in Multidisciplinary
Female drivers in Tabriz reported frequent verbal and non-verbal harassment while driving. Participants linked harassment to social and contextual factors and said it caused fear, reduced concentration, lower driving confidence, and sometimes temporary withdrawal
from driving.
|
Why it matters
Because harassment can lower confidence, increase anxiety and reduce concentration, it may distort young drivers' self-assessed skills and contribute to risky driving or avoidance, so consider measuring harassment and social-contextual factors in your study.
|
Read
the paper → |
|
|
|
| 07
|
Global burden and strength of evidence for 88 ris…
H. Li, H. Chen & D. Zheng et al. | 2026
The
Kaohsiung Journal of Medical Sciences |
Q1 · 88th percentile in Medicine (all)
Using GBD 1990–2021 data across 204 countries, the study found that childhood asthma deaths attributable to high BMI declined globally while DALYs increased, with females showing higher mortality and males higher DALYs; low-SDI countries bore higher mortality
burdens and high-SDI regions higher DALY burdens. Projections to 2035 indicate continued declines in mortality but rising DALYs, highlighting persistent sex- and SDI-related disparities.
|
Why it matters
This study provides sex- and SDI-stratified GBD estimates and future projections of high-BMI-attributable childhood asthma that are directly relevant for refining your global burden assessments and prioritizing risk-factor interventions.
|
Read
the paper → |
|
|
|
| 08
|
Self-assessed driving skills and risky driving be…
N. Haworth, F. Mansourifar & S. Kaye | 2026
| Vol. 99
Journal
of Safety Research |
Q1 · 87th percentile in Safety, Risk, Reliability and Quality
In surveys of Queensland e-scooter riders (2024–2025) knowledge of legal speed limits was low and worsened over time; riders often underestimated limits, but overestimating non-footpath limits was linked to lower perceived and reported compliance, with older/female
riders reporting higher compliance and frequent riders reporting lower compliance. Effect sizes were modest.
|
Why it matters
For research on self-assessed driving skills and risky driving in young drivers, this suggests that misperceptions of speed limits—particularly overestimation—can reduce compliance, implying that overconfidence or incorrect self-assessments may directly contribute
to risky speeding behaviours.
|
Read
the paper → |
|
|
|
| 09
|
Global burden of disorders affecting the nervous…
N. Mygind, G. Asiki & B. Cupido et al. | 2026
| Vol. 15, Issue 19
Journal
of the American Heart Association |
Q1 · 86th percentile in Cardiology and Cardiovascular Medicine
This review identifies major gaps in knowledge and care for cardiovascular conditions that disproportionately affect women—including MINOCA, SCAD, Takotsubo cardiomyopathy, coronary microvascular dysfunction, vasospastic angina, HFpEF, female hypertension,
and pregnancy-related complications—and calls for translational, sex-specific, and globally inclusive research to improve diagnosis, prevention, and treatment.
|
Why it matters
Because sex-specific cardiovascular diseases and pregnancy-related complications can drive neurological outcomes (e.g., stroke, vascular cognitive impairment) and skew population-level burden estimates, integrating female-focused cardiovascular data is important
for accurately assessing and addressing the global burden of nervous system disorders.
|
Read
the paper → |
|
|
|
| 10
|
Global burden and strength of evidence for 88 ris…
X. Zhou, X. Zhong & M. Liu et al. | 2026
| Vol. Volume 18
International
Journal of Women s Health |
Q1 · 85th percentile in Maternity and Midwifery
Global early-onset breast cancer incidence rose from 1990–2021 with prevalence growth accelerating after 2012, while mortality declined in high‑SDI regions but increased in low‑middle SDI regions; the 40–44 age group showed the fastest increases. High fasting
plasma glucose, smoking, and alcohol were the leading attributable risks, with some model-driven negative BMI PAFs in high‑SDI settings.
|
Why it matters
Because it provides GBD-derived, risk-specific population attributable fractions and SDI‑stratified trends, this analysis directly informs comparative burden estimates and strength-of-evidence assessment for the 88 GBD risk factors you study.
|
Read
the paper → |
|
|
Matches are generated from the research profile held for you in the platform database. Reply to this message to correct a topic.
Research Intelligence Platform · University of Nicosia · 46 Makedonitissas Ave, 2417 Nicosia, Cyprus
Unsubscribe
from the research digest
|
|
|